P24L (p.Pro24Leu) variant of CD274 (Programmed cell death 1 ligand 1)
P24L (p.Pro24Leu) in CD274 (Programmed cell death 1 ligand 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.37 / 1. The record also includes population frequency data and structural context.
P24L (p.Pro24Leu) variant details
- p.Pro24Leu
- gnomAD rs1416019385
- Missense
- Variant Prioritization Score for Impact Estimate 0.371
- REVEL 0.23
- AlphaMissense 0.20
- MetaLR 0.22
- MetaSVM -0.65
- CADD 22.90
- PolyPhen-2 0.70
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available