N35T (p.Asn35Thr) variant of CD274 (Programmed cell death 1 ligand 1)
N35T (p.Asn35Thr) in CD274 (Programmed cell death 1 ligand 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data and structural context.
N35T (p.Asn35Thr) variant details
- p.Asn35Thr
- ExAC rs780953696
- gnomAD rs780953696
- Missense
- Variant Prioritization Score for Impact Estimate 0.334
- REVEL 0.20
- AlphaMissense 0.20
- MetaLR 0.32
- MetaSVM -0.32
- CADD 25.10
- PolyPhen-2 0.89
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available