N17H (p.Asn17His) variant of CD274 (Programmed cell death 1 ligand 1)
N17H (p.Asn17His) in CD274 (Programmed cell death 1 ligand 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data and structural context.
N17H (p.Asn17His) variant details
- p.Asn17His
- Ensembl rs1819298628
- Missense
- Variant Prioritization Score for Impact Estimate 0.241
- REVEL 0.07
- AlphaMissense 0.06
- MetaLR 0.06
- MetaSVM -1.02
- CADD 9.12
- PolyPhen-2 0.01
- Most common in the African/African-American population (allele frequency 6e-05)
- Structural context available