M36W (p.Met36Trp) variant of CD274 (Programmed cell death 1 ligand 1)
M36W (p.Met36Trp) in CD274 (Programmed cell death 1 ligand 1) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data, published literature, and structural context.
M36W (p.Met36Trp) variant details
- p.Met36Trp
- gnomAD 9-5457121-A-ATGGT
- Frameshift
- Variant Prioritization Score for Impact Estimate 0.35
- CADD 23.30
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available