M36T (p.Met36Thr) variant of CD274 (Programmed cell death 1 ligand 1)
M36T (p.Met36Thr) in CD274 (Programmed cell death 1 ligand 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data and structural context.
M36T (p.Met36Thr) variant details
- p.Met36Thr
- gnomAD rs1283319713
- Missense
- Variant Prioritization Score for Impact Estimate 0.31
- REVEL 0.11
- AlphaMissense 0.29
- MetaLR 0.12
- MetaSVM -0.99
- CADD 23.20
- PolyPhen-2 0.01
- Most common in the Ashkenazi Jewish population (allele frequency 3.8e-05)
- Structural context available