M36L (p.Met36Leu) variant of CD274 (Programmed cell death 1 ligand 1)
M36L (p.Met36Leu) in CD274 (Programmed cell death 1 ligand 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data and structural context.
M36L (p.Met36Leu) variant details
- p.Met36Leu
- Ensembl rs2131211256
- Missense
- Variant Prioritization Score for Impact Estimate 0.283
- REVEL 0.09
- AlphaMissense 0.18
- MetaLR 0.11
- MetaSVM -1.01
- CADD 22.60
- PolyPhen-2 0.00
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available