M36K (p.Met36Lys) variant of CD274 (Programmed cell death 1 ligand 1)
M36K (p.Met36Lys) in CD274 (Programmed cell death 1 ligand 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data and structural context.
M36K (p.Met36Lys) variant details
- p.Met36Lys
- gnomAD rs1283319713
- Missense
- Variant Prioritization Score for Impact Estimate 0.399
- REVEL 0.27
- AlphaMissense 0.55
- MetaLR 0.13
- MetaSVM -0.83
- CADD 23.60
- PolyPhen-2 0.77
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available