M10L (p.Met10Leu) variant of CD274 (Programmed cell death 1 ligand 1)
M10L (p.Met10Leu) in CD274 (Programmed cell death 1 ligand 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.15 / 1. The record also includes population frequency data and structural context.
M10L (p.Met10Leu) variant details
- p.Met10Leu
- gnomAD rs1461605894
- Missense
- Variant Prioritization Score for Impact Estimate 0.154
- REVEL 0.10
- AlphaMissense 0.12
- MetaLR 0.07
- MetaSVM -1.03
- CADD 1.86
- PolyPhen-2 0.00
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available