L16M (p.Leu16Met) variant of CD274 (Programmed cell death 1 ligand 1)
L16M (p.Leu16Met) in CD274 (Programmed cell death 1 ligand 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data and structural context.
L16M (p.Leu16Met) variant details
- p.Leu16Met
- Ensembl rs2131208847
- Missense
- Variant Prioritization Score for Impact Estimate 0.244
- REVEL 0.13
- AlphaMissense 0.18
- MetaLR 0.13
- MetaSVM -0.93
- CADD 22.10
- PolyPhen-2 0.94
- Most common in the Non-Finnish European population (allele frequency 9.1e-07)
- Structural context available