L16L (p.Leu16Leu) variant of CD274 (Programmed cell death 1 ligand 1)
L16L (p.Leu16Leu) in CD274 (Programmed cell death 1 ligand 1) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data, published literature, and structural context.
L16L (p.Leu16Leu) variant details
- p.Leu16Leu
- rs2131208857
- gnomAD 9-5456161-G-A
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.231
- CADD 7.87
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available
- Literature evidence available