I38V (p.Ile38Val) variant of CD274 (Programmed cell death 1 ligand 1)
I38V (p.Ile38Val) in CD274 (Programmed cell death 1 ligand 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data and structural context.
I38V (p.Ile38Val) variant details
- p.Ile38Val
- TOPMed rs1213866118
- gnomAD rs1213866118
- Missense
- Variant Prioritization Score for Impact Estimate 0.24
- REVEL 0.02
- AlphaMissense 0.09
- MetaLR 0.01
- MetaSVM -0.92
- CADD 15.10
- PolyPhen-2 0.00
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available