I38T (p.Ile38Thr) variant of CD274 (Programmed cell death 1 ligand 1)
I38T (p.Ile38Thr) in CD274 (Programmed cell death 1 ligand 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data and structural context.
I38T (p.Ile38Thr) variant details
- p.Ile38Thr
- gnomAD rs761826556
- Missense
- Variant Prioritization Score for Impact Estimate 0.356
- REVEL 0.22
- AlphaMissense 0.48
- MetaLR 0.02
- MetaSVM -1.01
- CADD 23.60
- PolyPhen-2 0.20
- Most common in the Non-Finnish European population (allele frequency 3.6e-06)
- Structural context available