H14Y (p.His14Tyr) variant of CD274 (Programmed cell death 1 ligand 1)
H14Y (p.His14Tyr) in CD274 (Programmed cell death 1 ligand 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data and structural context.
H14Y (p.His14Tyr) variant details
- p.His14Tyr
- gnomAD rs1819298566
- Missense
- Variant Prioritization Score for Impact Estimate 0.328
- REVEL 0.09
- AlphaMissense 0.08
- MetaLR 0.10
- MetaSVM -0.98
- CADD 17.20
- PolyPhen-2 0.97
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available