G33S (p.Gly33Ser) variant of CD274 (Programmed cell death 1 ligand 1)
G33S (p.Gly33Ser) in CD274 (Programmed cell death 1 ligand 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.78 / 1. The record also includes population frequency data and structural context.
G33S (p.Gly33Ser) variant details
- p.Gly33Ser
- TOPMed rs1312762207
- gnomAD rs1312762207
- Missense
- Variant Prioritization Score for Impact Estimate 0.782
- REVEL 0.83
- AlphaMissense 0.23
- MetaLR 0.73
- MetaSVM 0.57
- CADD 26.70
- PolyPhen-2 1.00
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available