F7C (p.Phe7Cys) variant of CD274 (Programmed cell death 1 ligand 1)
F7C (p.Phe7Cys) in CD274 (Programmed cell death 1 ligand 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data and structural context.
F7C (p.Phe7Cys) variant details
- p.Phe7Cys
- gnomAD rs1401088731
- Missense
- Variant Prioritization Score for Impact Estimate 0.293
- REVEL 0.18
- AlphaMissense 0.15
- MetaLR 0.20
- MetaSVM -0.84
- CADD 22.90
- PolyPhen-2 1.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available