E39G (p.Glu39Gly) variant of CD274 (Programmed cell death 1 ligand 1)
E39G (p.Glu39Gly) in CD274 (Programmed cell death 1 ligand 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.43 / 1. The record also includes population frequency data and structural context.
E39G (p.Glu39Gly) variant details
- p.Glu39Gly
- gnomAD rs1461816349
- Missense
- Variant Prioritization Score for Impact Estimate 0.429
- REVEL 0.34
- AlphaMissense 0.23
- MetaLR 0.38
- MetaSVM -0.35
- CADD 26.10
- PolyPhen-2 1.00
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available