E31A (p.Glu31Ala) variant of CD274 (Programmed cell death 1 ligand 1)
E31A (p.Glu31Ala) in CD274 (Programmed cell death 1 ligand 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data and structural context.
E31A (p.Glu31Ala) variant details
- p.Glu31Ala
- ExAC rs778185448
- gnomAD rs778185448
- Missense
- Variant Prioritization Score for Impact Estimate 0.38
- REVEL 0.23
- AlphaMissense 0.16
- MetaLR 0.20
- MetaSVM -0.95
- CADD 25.00
- PolyPhen-2 0.69
- Most common in the Non-Finnish European population (allele frequency 4.5e-06)
- Structural context available