D26E (p.Asp26Glu) variant of CD274 (Programmed cell death 1 ligand 1)
D26E (p.Asp26Glu) in CD274 (Programmed cell death 1 ligand 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data and structural context.
D26E (p.Asp26Glu) variant details
- p.Asp26Glu
- Ensembl rs2131211048
- Missense
- Variant Prioritization Score for Impact Estimate 0.191
- REVEL 0.06
- AlphaMissense 0.14
- MetaLR 0.08
- MetaSVM -1.02
- CADD 15.00
- PolyPhen-2 0.00
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available