A5P (p.Ala5Pro) variant of CD274 (Programmed cell death 1 ligand 1)
A5P (p.Ala5Pro) in CD274 (Programmed cell death 1 ligand 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.11 / 1. The record also includes population frequency data and structural context.
A5P (p.Ala5Pro) variant details
- p.Ala5Pro
- cosmic curated COSV10105
- 1000Genomes rs139709512
- ESP rs139709512
- ExAC rs139709512
- Missense
- Variant Prioritization Score for Impact Estimate 0.106
- REVEL 0.03
- AlphaMissense 0.15
- MetaLR 0.05
- MetaSVM -0.96
- CADD 2.29
- PolyPhen-2 0.00
- Most common in the HGDP:BIAKA population (allele frequency 0.14)
- Structural context available