A18S (p.Ala18Ser) variant of CD274 (Programmed cell death 1 ligand 1)
A18S (p.Ala18Ser) in CD274 (Programmed cell death 1 ligand 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.42 / 1. The record also includes population frequency data, published literature, and structural context.
A18S (p.Ala18Ser) variant details
- p.Ala18Ser
- gnomAD 9-5456165-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.422
- REVEL 0.16
- AlphaMissense 0.21
- MetaLR 0.27
- MetaSVM -0.57
- CADD 34.00
- PolyPhen-2 1.00
- Population evidence available
- Structural context available
- Literature evidence available