A18E (p.Ala18Glu) variant of CD274 (Programmed cell death 1 ligand 1)
A18E (p.Ala18Glu) in CD274 (Programmed cell death 1 ligand 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data and structural context.
A18E (p.Ala18Glu) variant details
- p.Ala18Glu
- Ensembl rs2131210878
- Missense
- Variant Prioritization Score for Impact Estimate 0.408
- REVEL 0.20
- AlphaMissense 0.64
- MetaLR 0.02
- MetaSVM -0.94
- CADD 27.60
- PolyPhen-2 1.00
- Population evidence available
- Structural context available