V8L (p.Val8Leu) variant of CD2 (T-cell surface antigen CD2)
V8L (p.Val8Leu) in CD2 (T-cell surface antigen CD2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.13 / 1. The record also includes population frequency data and structural context.
V8L (p.Val8Leu) variant details
- p.Val8Leu
- TOPMed rs1651769569
- gnomAD rs1651769569
- Missense
- Variant Prioritization Score for Impact Estimate 0.131
- REVEL 0.14
- MetaLR 0.05
- MetaSVM -0.95
- CADD 0.01
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available