T77I (p.Thr77Ile) variant of CD2 (T-cell surface antigen CD2)
T77I (p.Thr77Ile) in CD2 (T-cell surface antigen CD2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.13 / 1. The record also includes population frequency data, published literature, and structural context.
T77I (p.Thr77Ile) variant details
- p.Thr77Ile
- gnomAD 1-116754799-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.13
- REVEL 0.14
- MetaLR 0.07
- MetaSVM -0.90
- CADD 0.00
- PolyPhen-2 0.19
- SIFT 0.52
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available
- Literature evidence available