S47G (p.Ser47Gly) variant of CD2 (T-cell surface antigen CD2)
S47G (p.Ser47Gly) in CD2 (T-cell surface antigen CD2) is a missense change. Clinical records from ClinVar, EBI, and UniProt describe it as likely benign in the context of not specified. The available variant effect predictions contribute to a CATVariant prioritization score of 0.09 / 1. The record also includes population frequency data and structural context.
S47G (p.Ser47Gly) variant details
- p.Ser47Gly
- rs1447057669
- ClinGen CA341839537
- ClinVar RCV004433296
- TOPMed rs1447057669
- Likely benign
- not specified
- Missense
- Variant Prioritization Score for Impact Estimate 0.0938
- REVEL 0.07
- MetaLR 0.02
- MetaSVM -1.05
- CADD 0.18
- PolyPhen-2 0.00
- SIFT 1.00
- ClinVar: Likely benign (not specified)
- EBI: Likely benign
- UniProt: Likely benign
- Most common in the Non-Finnish European population (allele frequency 7.3e-05)
- Structural context available