S19P (p.Ser19Pro) variant of CD2 (T-cell surface antigen CD2)
S19P (p.Ser19Pro) in CD2 (T-cell surface antigen CD2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data and structural context.
S19P (p.Ser19Pro) variant details
- p.Ser19Pro
- ExAC rs778816590
- TOPMed rs778816590
- gnomAD rs778816590
- Missense
- Variant Prioritization Score for Impact Estimate 0.242
- REVEL 0.30
- MetaLR 0.24
- MetaSVM -0.68
- CADD 9.40
- PolyPhen-2 0.00
- SIFT 0.14
- Most common in the Latino/Admixed American population (allele frequency 0.00016)
- Structural context available