S10N (p.Ser10Asn) variant of CD2 (T-cell surface antigen CD2)
S10N (p.Ser10Asn) in CD2 (T-cell surface antigen CD2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.37 / 1. The record also includes population frequency data, published literature, and structural context.
S10N (p.Ser10Asn) variant details
- p.Ser10Asn
- gnomAD 1-116754521-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.374
- REVEL 0.31
- MetaLR 0.51
- MetaSVM -0.33
- CADD 18.00
- PolyPhen-2 0.31
- SIFT 0.14
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available
- Literature evidence available