S10I (p.Ser10Ile) variant of CD2 (T-cell surface antigen CD2)
S10I (p.Ser10Ile) in CD2 (T-cell surface antigen CD2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.50 / 1. The record also includes population frequency data and structural context.
S10I (p.Ser10Ile) variant details
- p.Ser10Ile
- TOPMed rs906824892
- gnomAD rs906824892
- Missense
- Variant Prioritization Score for Impact Estimate 0.502
- REVEL 0.54
- MetaLR 0.52
- MetaSVM -0.29
- CADD 22.70
- PolyPhen-2 0.92
- SIFT 0.04
- Most common in the African/African-American population (allele frequency 6e-05)
- Structural context available