Q49E (p.Gln49Glu) variant of CD2 (T-cell surface antigen CD2)
Q49E (p.Gln49Glu) in CD2 (T-cell surface antigen CD2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.13 / 1. The record also includes population frequency data and structural context.
Q49E (p.Gln49Glu) variant details
- p.Gln49Glu
- TOPMed rs1287434511
- gnomAD rs1287434511
- Missense
- Variant Prioritization Score for Impact Estimate 0.133
- REVEL 0.14
- MetaLR 0.10
- MetaSVM -0.95
- CADD 1.52
- PolyPhen-2 0.14
- SIFT 0.18
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available