P46L (p.Pro46Leu) variant of CD2 (T-cell surface antigen CD2)
P46L (p.Pro46Leu) in CD2 (T-cell surface antigen CD2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data and structural context.
P46L (p.Pro46Leu) variant details
- p.Pro46Leu
- ExAC rs752907362
- gnomAD rs752907362
- Missense
- Variant Prioritization Score for Impact Estimate 0.237
- REVEL 0.14
- MetaLR 0.25
- MetaSVM -0.80
- CADD 20.80
- PolyPhen-2 0.93
- SIFT 0.00
- Most common in the East Asian population (allele frequency 7.6e-05)
- Structural context available