P46A (p.Pro46Ala) variant of CD2 (T-cell surface antigen CD2)
P46A (p.Pro46Ala) in CD2 (T-cell surface antigen CD2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.13 / 1. The record also includes population frequency data and structural context.
P46A (p.Pro46Ala) variant details
- p.Pro46Ala
- cosmic curated COSV10104
- 1000Genomes rs142374557
- ESP rs142374557
- ExAC rs142374557
- Missense
- Variant Prioritization Score for Impact Estimate 0.134
- REVEL 0.13
- MetaLR 0.10
- MetaSVM -1.05
- CADD 5.05
- PolyPhen-2 0.11
- SIFT 0.06
- Most common in the HGDP:ORCADIAN population (allele frequency 0.071)
- Structural context available