N42S (p.Asn42Ser) variant of CD2 (T-cell surface antigen CD2)
N42S (p.Asn42Ser) in CD2 (T-cell surface antigen CD2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.11 / 1. The record also includes population frequency data and structural context.
N42S (p.Asn42Ser) variant details
- p.Asn42Ser
- ExAC rs773856061
- TOPMed rs773856061
- gnomAD rs773856061
- Missense
- Variant Prioritization Score for Impact Estimate 0.11
- REVEL 0.08
- MetaLR 0.07
- MetaSVM -0.99
- CADD 5.51
- PolyPhen-2 0.01
- SIFT 0.17
- Most common in the Middle Eastern population (allele frequency 0.00017)
- Structural context available