M50V (p.Met50Val) variant of CD2 (T-cell surface antigen CD2)
M50V (p.Met50Val) in CD2 (T-cell surface antigen CD2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.10 / 1. The record also includes population frequency data, published literature, and structural context.
M50V (p.Met50Val) variant details
- p.Met50Val
- gnomAD 1-116754717-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.104
- REVEL 0.10
- MetaLR 0.06
- MetaSVM -1.03
- CADD 0.11
- PolyPhen-2 0.03
- SIFT 0.26
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available
- Literature evidence available