L37S (p.Leu37Ser) variant of CD2 (T-cell surface antigen CD2)
L37S (p.Leu37Ser) in CD2 (T-cell surface antigen CD2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.37 / 1. The record also includes population frequency data and structural context.
L37S (p.Leu37Ser) variant details
- p.Leu37Ser
- ExAC rs775203706
- gnomAD rs775203706
- Missense
- Variant Prioritization Score for Impact Estimate 0.373
- REVEL 0.28
- MetaLR 0.29
- MetaSVM -0.73
- CADD 23.20
- PolyPhen-2 0.98
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available