L12R (p.Leu12Arg) variant of CD2 (T-cell surface antigen CD2)
L12R (p.Leu12Arg) in CD2 (T-cell surface antigen CD2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.59 / 1. The record also includes population frequency data, published literature, and structural context.
L12R (p.Leu12Arg) variant details
- p.Leu12Arg
- gnomAD 1-116754527-T-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.588
- REVEL 0.60
- MetaLR 0.55
- MetaSVM -0.24
- CADD 24.20
- PolyPhen-2 0.96
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available