K85R (p.Lys85Arg) variant of CD2 (T-cell surface antigen CD2)
K85R (p.Lys85Arg) in CD2 (T-cell surface antigen CD2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.13 / 1. The record also includes population frequency data and structural context.
K85R (p.Lys85Arg) variant details
- p.Lys85Arg
- 1000Genomes rs181664416
- ExAC rs181664416
- TOPMed rs181664416
- gnomAD rs181664416
- Missense
- Variant Prioritization Score for Impact Estimate 0.133
- REVEL 0.10
- MetaLR 0.08
- MetaSVM -0.99
- CADD 9.23
- PolyPhen-2 0.13
- SIFT 0.27
- Most common in the 1KG:CHS population (allele frequency 0.0049)
- Structural context available