K75E (p.Lys75Glu) variant of CD2 (T-cell surface antigen CD2)
K75E (p.Lys75Glu) in CD2 (T-cell surface antigen CD2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.15 / 1. The record also includes population frequency data, published literature, and structural context.
K75E (p.Lys75Glu) variant details
- p.Lys75Glu
- gnomAD 1-116754792-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.155
- REVEL 0.14
- MetaLR 0.11
- MetaSVM -0.99
- CADD 8.58
- PolyPhen-2 0.28
- SIFT 0.23
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available
- Literature evidence available