K67N (p.Lys67Asn) variant of CD2 (T-cell surface antigen CD2)
K67N (p.Lys67Asn) in CD2 (T-cell surface antigen CD2) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data and structural context.
K67N (p.Lys67Asn) variant details
- p.Lys67Asn
- NCI-TCGA TCGA novel
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.231
- REVEL 0.17
- MetaLR 0.23
- MetaSVM -0.92
- CADD 16.60
- PolyPhen-2 0.78
- SIFT 0.10
- UniProt: Variant assessed as somatic; moderate impact.
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available