K25Q (p.Lys25Gln) variant of CD2 (T-cell surface antigen CD2)
K25Q (p.Lys25Gln) in CD2 (T-cell surface antigen CD2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data, published literature, and structural context.
K25Q (p.Lys25Gln) variant details
- p.Lys25Gln
- gnomAD 1-116754642-A-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.139
- REVEL 0.16
- MetaLR 0.09
- MetaSVM -1.01
- CADD 0.00
- PolyPhen-2 0.07
- SIFT 0.44
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available