K20Q (p.Lys20Gln) variant of CD2 (T-cell surface antigen CD2)
K20Q (p.Lys20Gln) in CD2 (T-cell surface antigen CD2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data, published literature, and structural context.
K20Q (p.Lys20Gln) variant details
- p.Lys20Gln
- gnomAD 1-116754550-A-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.224
- REVEL 0.25
- MetaLR 0.33
- MetaSVM -0.72
- CADD 9.57
- PolyPhen-2 0.20
- SIFT 0.11
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available
- Literature evidence available