K20E (p.Lys20Glu) variant of CD2 (T-cell surface antigen CD2)
K20E (p.Lys20Glu) in CD2 (T-cell surface antigen CD2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data and structural context.
K20E (p.Lys20Glu) variant details
- p.Lys20Glu
- TOPMed rs1349995035
- gnomAD rs1349995035
- Missense
- Variant Prioritization Score for Impact Estimate 0.254
- REVEL 0.28
- MetaLR 0.42
- MetaSVM -0.61
- CADD 10.70
- PolyPhen-2 0.39
- SIFT 0.15
- Most common in the African/African-American population (allele frequency 4.8e-05)
- Structural context available