I57V (p.Ile57Val) variant of CD2 (T-cell surface antigen CD2)
I57V (p.Ile57Val) in CD2 (T-cell surface antigen CD2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data and structural context.
I57V (p.Ile57Val) variant details
- p.Ile57Val
- ExAC rs769613740
- TOPMed rs769613740
- gnomAD rs769613740
- Missense
- Variant Prioritization Score for Impact Estimate 0.282
- REVEL 0.14
- MetaLR 0.08
- MetaSVM -1.07
- CADD 6.01
- PolyPhen-2 0.26
- SIFT 0.36
- Most common in the Finnish in Finland (FIN) population (allele frequency 9.4e-05)
- Structural context available