I57T (p.Ile57Thr) variant of CD2 (T-cell surface antigen CD2)
I57T (p.Ile57Thr) in CD2 (T-cell surface antigen CD2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data, published literature, and structural context.
I57T (p.Ile57Thr) variant details
- p.Ile57Thr
- gnomAD 1-116754739-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.321
- REVEL 0.26
- MetaLR 0.24
- MetaSVM -0.81
- CADD 22.20
- PolyPhen-2 1.00
- SIFT 0.07
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available
- Literature evidence available