I54T (p.Ile54Thr) variant of CD2 (T-cell surface antigen CD2)
I54T (p.Ile54Thr) in CD2 (T-cell surface antigen CD2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data, published literature, and structural context.
I54T (p.Ile54Thr) variant details
- p.Ile54Thr
- gnomAD 1-116754730-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.282
- REVEL 0.04
- MetaLR 0.12
- MetaSVM -0.99
- CADD 2.52
- PolyPhen-2 0.14
- SIFT 0.16
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available