I45V (p.Ile45Val) variant of CD2 (T-cell surface antigen CD2)
I45V (p.Ile45Val) in CD2 (T-cell surface antigen CD2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data and structural context.
I45V (p.Ile45Val) variant details
- p.Ile45Val
- ExAC rs754207272
- gnomAD rs754207272
- Missense
- Variant Prioritization Score for Impact Estimate 0.192
- REVEL 0.20
- MetaLR 0.22
- MetaSVM -0.85
- CADD 7.76
- PolyPhen-2 0.74
- SIFT 0.13
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available