I45T (p.Ile45Thr) variant of CD2 (T-cell surface antigen CD2)
I45T (p.Ile45Thr) in CD2 (T-cell surface antigen CD2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data and structural context.
I45T (p.Ile45Thr) variant details
- p.Ile45Thr
- ExAC rs755341854
- gnomAD rs755341854
- Missense
- Variant Prioritization Score for Impact Estimate 0.358
- REVEL 0.40
- MetaLR 0.29
- MetaSVM -0.75
- CADD 19.80
- PolyPhen-2 0.97
- SIFT 0.05
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available