I41T (p.Ile41Thr) variant of CD2 (T-cell surface antigen CD2)
I41T (p.Ile41Thr) in CD2 (T-cell surface antigen CD2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data and structural context.
I41T (p.Ile41Thr) variant details
- p.Ile41Thr
- TOPMed rs1478852347
- gnomAD rs1478852347
- Missense
- Variant Prioritization Score for Impact Estimate 0.295
- REVEL 0.23
- MetaLR 0.07
- MetaSVM -1.08
- CADD 22.60
- PolyPhen-2 0.67
- SIFT 0.03
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available