I14V (p.Ile14Val) variant of CD2 (T-cell surface antigen CD2)
I14V (p.Ile14Val) in CD2 (T-cell surface antigen CD2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data and structural context.
I14V (p.Ile14Val) variant details
- p.Ile14Val
- gnomAD rs1362083973
- Missense
- Variant Prioritization Score for Impact Estimate 0.258
- REVEL 0.28
- MetaLR 0.28
- MetaSVM -0.69
- CADD 8.21
- PolyPhen-2 0.18
- SIFT 0.03
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available