G38D (p.Gly38Asp) variant of CD2 (T-cell surface antigen CD2)
G38D (p.Gly38Asp) in CD2 (T-cell surface antigen CD2) is a missense change. Clinical records from ClinVar, EBI, and UniProt describe it as likely benign in the context of not specified. The available variant effect predictions contribute to a CATVariant prioritization score of 0.09 / 1. The record also includes population frequency data and structural context.
G38D (p.Gly38Asp) variant details
- p.Gly38Asp
- rs762609016
- ClinGen CA1027030
- ClinVar RCV004341710
- ExAC rs762609016
- Likely benign
- not specified
- Missense
- Variant Prioritization Score for Impact Estimate 0.086
- REVEL 0.05
- MetaLR 0.02
- MetaSVM -1.04
- CADD 0.10
- PolyPhen-2 0.04
- SIFT 1.00
- ClinVar: Likely benign (not specified)
- EBI: Likely benign
- UniProt: Likely benign
- Most common in the South Asian population (allele frequency 3.5e-05)
- Structural context available