G35V (p.Gly35Val) variant of CD2 (T-cell surface antigen CD2)
G35V (p.Gly35Val) in CD2 (T-cell surface antigen CD2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.47 / 1. The record also includes population frequency data, published literature, and structural context.
G35V (p.Gly35Val) variant details
- p.Gly35Val
- gnomAD 1-116754673-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.466
- REVEL 0.43
- MetaLR 0.25
- MetaSVM -0.56
- CADD 23.20
- PolyPhen-2 1.00
- SIFT 0.02
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available
- Literature evidence available