F78L (p.Phe78Leu) variant of CD2 (T-cell surface antigen CD2)
F78L (p.Phe78Leu) in CD2 (T-cell surface antigen CD2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data and structural context.
F78L (p.Phe78Leu) variant details
- p.Phe78Leu
- gnomAD rs1334824140
- Missense
- Variant Prioritization Score for Impact Estimate 0.141
- REVEL 0.17
- MetaLR 0.06
- MetaSVM -0.96
- CADD 0.03
- PolyPhen-2 0.01
- SIFT 0.60
- Most common in the South Asian population (allele frequency 2.3e-05)
- Structural context available